The Fisher Chemical a0560fp21 acetone reference describes an HPLC grade solvent designed for analytical and preparative separations where low impurities and consistent performance are critical. Laboratories rely on this product grade to support method validation, compound identification, and sensitive sample preparation across pharmaceutical, environmental, and industrial testing workflows.
Below is a structured overview that highlights how the specification, regulatory profile, packaging options, and typical applications align for a0560fp21 acetone from Fisher Chemical.
| Property | Specification | Testing Method | Typical Result |
|---|---|---|---|
| Purity | Minimum 99.9% | GC Headspace | 99.95% |
| Water Content | Maximum 0.2% | Karl Fischer Titration | 0.06% |
| Residual Solvents | Meets HPLC Grade limits | GC Trace Analysis | Within specification |
| Particulate Matter | Filtered 0.2 µm | Visual Inspection | Clear, particle free |
Analytical Performance Characteristics
For method development and method transfer, understanding the key performance indicators of a0560fp21 acetone is essential. Fisher Chemical formulates this product to support sensitive detection and reproducible retention times in reversed phase and normal phase chromatography.
Low absorbance across common UV wavelengths helps reduce baseline noise, enabling detection limits suitable for trace level analysis. Consistent water control minimizes peak tailing for basic and acidic analytes, improving peak shape and quantitation accuracy.
Regulatory and Quality Documentation
Regulatory and quality teams rely on comprehensive documentation to validate that a0560fp21 acetone meets the requirements of their methods and compliance frameworks. Fisher Chemical provides a detailed Certificate of Analysis, a stringent Manufacturing Practices statement, and relevant test reports on request.
Material compatibility guidance is included for common laboratory containers and autosampler vials, supporting method robustness and instrument system suitability checks.
Packaging and Handling Guidelines
Proper storage and handling procedures protect the integrity of a0560fp21 acetone and ensure analyst safety. Sealed glass containers minimize atmospheric contamination, while amber packaging reduces photo-degradation for longer shelf life under recommended storage conditions.
Handling guidance covers flammability risks, personal protective equipment, ventilation requirements, and procedures for safe dispensing and waste segregation in line with local chemical safety regulations.
Applications in Quantitative Analysis
Laboratories use a0560fp21 acetone as a mobile phase modifier, extraction solvent, and cleaning agent for analytical instrumentation. Its controlled impurity profile supports quantitative results in critical workflows such as residual solvent analysis, pharmaceutical dissolution testing, and environmental monitoring.
When paired with validated LC or GC methods, this solvent grade contributes to accurate concentration reporting, method reproducibility, and compliance with quality standards across regulated environments.
Key Takeaways for Method Development and Validation
- Check the Certificate of Analysis for batch specific purity and water content data.
- Confirm compatibility with your LC or GC system by matching wavelength and impurity profiles.
- Follow storage and handling guidance to preserve solvent integrity and ensure reproducible results.
- Use validated cleaning procedures for instruments to prevent cross-contamination between runs.
- Document lot numbers and QC checks as part of your method validation and audit trail.
FAQ
Reader questions
Is a0560fp21 acetone suitable for HPLC method development?
Yes, this HPLC grade acetone is formulated for method development and offers low UV absorbance and controlled impurities to support sensitive and reproducible chromatography.
What documentation is available for regulatory validation of a0560fp21 acetone?
Fisher Chemical provides a Certificate of Analysis, a GMP statement, and validation test reports that cover purity, water content, and particulate matter.
How should a0560fp21 acetone be stored to maintain its specified purity?
Store in a cool, dry, and well-ventilated area, sealed from atmospheric moisture and light, following the storage conditions detailed in the product documentation.
What personal protective equipment is required when handling this product?
Use appropriate gloves, safety goggles, and work in a certified fume hood to manage flammability and vapor exposure in compliance with local safety regulations.